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Last updated: 2014/10/20
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TGFB1 monoclonal antibody, clone 2C6

  • Catalog # : MAB6319
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native TGFB1.
  • Immunogen:
  • Native purified human platelets TGFB1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with the dimeric (25 KDa) and monomeric (12.5 KDa) forms of TGFB1 under both non-reducing and reducing conditions respectively.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (50-500 ng/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 10 mM PBS, pH 7.0
  • Storage Instruction:
  • Store at -20°C.
    Aliquot after reconstitution to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • ELISA
  • Inhibition Assay
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • ELISA
  • Inhibition Assay
  • Gene Information
  • Entrez GeneID:
  • 7040
  • Gene Name:
  • TGFB1
  • Gene Alias:
  • CED,DPD1,TGFB,TGFbeta
  • Gene Description:
  • transforming growth factor, beta 1
  • Gene Summary:
  • TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM
  • Other Designations:
  • TGF-beta 1 protein,diaphyseal dysplasia 1, progressive,transforming growth factor-beta 1
  • Interactome
  • Interactome
  • Related Disease
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