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Last updated: 2014/11/16
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MMP3 monoclonal antibody, clone SB14d (HRP)

  • Catalog # : MAB5894
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant MMP3.
  • Immunogen:
  • Recombinant protein corresponding to human MMP3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • human MMP-3; Does not cross react to human MMP-1, MMP-2 or MMP-9.
  • Form:
  • Liquid
  • Conjugation:
  • HRP
  • Concentration:
  • Lot specific
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • ELISA (1:1000-1:4000)
    Immunohistochemistry (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Paraffin embedded sections of human colon carcinoma were stained with MMP3 monoclonal antibody, clone SB14d. Goat Anti-Mouse IgG2a, human ads-BIOT and Streptavidin-HRP were used and then developed with DAB.
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4314
  • Gene Name:
  • MMP3
  • Gene Alias:
  • CHDS6,MGC126102,MGC126103,MGC126104,MMP-3,SL-1,STMY,STMY1,STR1
  • Gene Description:
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
  • Other Designations:
  • matrix metalloproteinase 3,matrix metalloproteinase 3 (stromelysin 1, progelatinase),progelatinase,proteoglycanase,stromelysin 1,transin-1
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