Monocytes and immunoaffinity purified soluble human CD14.
Bovine, Horse, Human, Pig
biG 10 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
The optimal working dilution should be determined by the end user.
Lyophilized from PBS
Store at -20°C for short term storage. For long term storage, store at -80°C. Reconstituted form should be stored at -20°C or with carrier protein (0.1% BSA) for long term. Avoid repeated freezing and thawing.
CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq