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KLK3 monoclonal antibody, clone 5A6 (HRP)

  • Catalog # : MAB5475
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native KLK3.
  • Immunogen:
  • Native purified KLK3 from human seminal plasma.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Specific for total PSA in equimolar determination, epitope 6. No cross-reactivity with human kallikrein 2.
  • Form:
  • Liquid
  • Conjugation:
  • HRP
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 5% BSA, 0.05% proclin 300)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Enzyme Immunoassay
  • Application Image
  • Enzyme Immunoassay
  • Gene Information
  • Entrez GeneID:
  • 354
  • Gene Name:
  • KLK3
  • Gene Alias:
  • APS,KLK2A1,PSA,hK3
  • Gene Description:
  • kallikrein-related peptidase 3
  • Gene Summary:
  • Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • P-30 antigen,gamma-seminoprotein,kallikrein 3, (prostate specific antigen),prostate specific antigen,semenogelase,seminin
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