KLK3 monoclonal antibody, clone 906 (HRP)
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Specification
Product Description
Mouse monoclonal antibody raised against KLK3.
Immunogen
Human KLK3.
Host
Mouse
Reactivity
Human
Specificity
human Prostate-specific antigen. No cross reactivity with human Albumin, AFP, CEA, PAP, CA-125, CA 19-9 or CA 15-3.
Form
Liquid
Conjugation
HRP
Isotype
IgG1
Recommend Usage
ELISA (>1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM potassium phosphate buffer, 0.085% NaCl, pH 7.2 (BSA, proclin)
Storage Instruction
Store at 4°C. Do not freeze.
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Applications
Enzyme-linked Immunoabsorbent Assay
Enzyme Immunoassay
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Gene Info — KLK3
Entrez GeneID
354Gene Name
KLK3
Gene Alias
APS, KLK2A1, PSA, hK3
Gene Description
kallikrein-related peptidase 3
Omim ID
176820Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
P-30 antigen|gamma-seminoprotein|kallikrein 3, (prostate specific antigen)|prostate specific antigen|semenogelase|seminin
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Interactome
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Pathway
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Disease
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