CGA monoclonal antibody, clone INN-hFSH-132
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Specification
Product Description
Mouse monoclonal antibody raised against native CGA.
Immunogen
Native purified CGA from human Follicle Stimulating Hormone (FSH).
Host
Mouse
Reactivity
Human
Specificity
A high affinity antibody recognising the alpha 4 epitope of the alpha-subunit of human Chorionic Gonadotrophin (hCG), hLH, hFSH, hTSH and free alpha-subunit. The recognized epitope comprises amino-acids alpha 15 to alpha 22 of the human sequence. Can be used in combination with INN-hCG-2, 22, 24, 32, 72 and INN-hFSH-6 and 60. This antibody will not cross-react with glycoprotein hormones of various animal species.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Radioimmunoassay
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Gene Info — CGA
Entrez GeneID
1081Gene Name
CGA
Gene Alias
CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA
Gene Description
glycoprotein hormones, alpha polypeptide
Omim ID
118850Gene Ontology
HyperlinkGene Summary
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. [provided by RefSeq
Other Designations
OTTHUMP00000016825|chorionic gonadotropin, alpha polypeptide|follicle-stimulating hormone alpha subunit
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