Mouse monoclonal antibody raised against native CD40LG.
Native purified CD40LG from mouse myeloma cell line transfected with human CD40LG.
TRAP1.3.6 recognizes the human CD154 cell surface antigen, a 32kD glycoprotein also known as CD40 ligand. CD154 is expressed on activated T lymphocytes, predominantly CD4 +ve and also on some basophils and mast cells.TRAP1.3.6 binds to CD154 at an epitope distinct from the CD40 binding site.
Flow Cytometry (10 ul of the suggested working dilution (1:10-1:50) to label 106 cells in 100 ul) The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (0.09% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq