Mouse monoclonal antibody raised against native CD14.
Native purified human CD14.
Theoretical MW (kDa):
This antibody reacts with CD14, a 53-55 KDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. This antibody also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
Flow Cytometry (1:1000) The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (15 mM sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq