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Last updated: 2014/7/21
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NCAM1 monoclonal antibody, clone B-A19

  • Catalog # : MAB4989
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native NCAM1.
  • Immunogen:
  • Native purified NCAM1 from human U937 cell line.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The CD56 antigen is a 175-185 KDa isoform of the neural cell adhesion molecule (NCAM). It is expressed by lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors. It is expressed on natural killer (NK) Cells and a subpopulation of T lymphocytes. NK cells make up approximately 10-25% of peripheral blood lymphocytes. Expression of neural cell adhesion molecules (N-CAM) provides neurons with a means of attaching to and interacting with other cells and the extracellular matrix. Alternative splicing of N-CAM mRNA results in several N-CAM isoforms. The three major isoforms are referred to as 180 kD, 140 kD, and 120 kD. Individual isoforms undergo various post-translational modifications, including the addition of polysialic acid residues to embryonic forms. The highly polysialylated forms of N-CAM present in embryos and neonates are lost during maturation and replaced by less-polysialic acid-laden mature forms of N-CAM. The functional significan
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (20 ul/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4684
  • Gene Name:
  • NCAM1
  • Gene Alias:
  • CD56,MSK39,NCAM
  • Gene Description:
  • neural cell adhesion molecule 1
  • Other Designations:
  • antigen recognized by monoclonal antibody 5.1H11,neural cell adhesion molecule, NCAM
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