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Last updated: 2014/12/14
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ABI1 monoclonal antibody, clone 4E2

  • Catalog # : MAB4909
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ABI1.
  • Immunogen:
  • Recombinant protein corresponding to human ABI1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Cross-reacts with human, rat and mouse. This antibody was developed against the spectrin SH3 domain binding protein Hssh3bp1. Hssh3bp1 is a marker of macropinocytic vesicles and a potential regulator of macropinocytosis. The gene encoding Hssh3bp1 has a role as a tumor suppressor gene which is inactivated during prostate tumorigenesis.
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Western Blot (1:1000-1:2000)
    Immunofluorescence (1:100-1:500)
    Immunohistochemistry (Frozen sections) (1:40-1:100)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:40-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Gene Information
  • Gene Name:
  • ABI1
  • Gene Alias:
  • ABI-1,E3B1,NAP1BP,SSH3BP,SSH3BP1
  • Gene Description:
  • abl-interactor 1
  • Gene Summary:
  • The protein encoded by this gene has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Abelson interactor 1,Abl-interactor protein 1 long,OTTHUMP00000019352,OTTHUMP00000019355,eps8 binding protein,interactor protein AblBP4,nap1 binding protein,spectrin SH3 domain binding protein 1
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