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Last updated: 2016/9/25
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CD80 monoclonal antibody, clone MAB104

  • Catalog # : MAB4670
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD80.
  • Immunogen:
  • Native purified CD80 from Jijoye cells (Human Burkitt Lymphoma cell line).
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • B cell activation antigen B7-1 is also called BB1 and clustered as CD80 during the 5th Leucocyte Typing workshop. CD80 is a member of the Ig superfamily and serves as the ligand for two T-cell molecules, CD28 and CD152 (CTLA-4). Reacts with in vitro activated normal B cells. Reacts weakly with a small proportion of non-activated normal B cells. Does not react with peripheral monocytes, resting and activated normal T cells, T-cell lines and T-cell clones. The molecular weight of the recognized antigen is 60KDa.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunofluorescence (2ug/5x105 cells/test)
    Flow Cytometry (2ug/5x105 cells/test)
    Immunohistochemistry (Frozen sections)(1:20-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS (1mg/mL BSA)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 941
  • Gene Name:
  • CD80
  • Gene Alias:
  • CD28LG,CD28LG1,LAB7
  • Gene Description:
  • CD80 molecule
  • Gene Summary:
  • The B-lymphocyte activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells.[supplied by OMIM
  • Other Designations:
  • B-lymphocyte activation antigen B7,CD80 antigen,CD80 antigen (CD28 antigen ligand 1, B7-1 antigen),costimulatory factor CD80,costimulatory molecule variant IgV-CD80
  • Interactome
  • Interactome
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