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Last updated: 2014/7/14
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F8 monoclonal antibody, clone 012

  • Catalog # : MAB4086
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial F8.
  • Immunogen:
  • Human F8 A2 domain.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Binds human factor VIII and human factor VIIIa in solid-phase ELISA. Antibody binds human factor VIII A2 domain in immunoblotting techniques.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 10 mM sodium phosphate buffer, 150 mM NaCl, pH 7.4 (0.01% sodium azide)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with distilled water, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • ELISA
  • Enzyme Immunoassay
  • Application Image
  • Western Blot
  • ELISA
  • Enzyme Immunoassay
  • Gene Information
  • Entrez GeneID:
  • 2157
  • Gene Name:
  • F8
  • Gene Alias:
  • AHF,DXS1253E,F8B,F8C,FVIII,HEMA
  • Gene Description:
  • coagulation factor VIII, procoagulant component
  • Gene Summary:
  • This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000061446,OTTHUMP00000196174,coagulation factor VIII,coagulation factor VIIIc,factor VIII F8B,procoagulant component
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