CD4 monoclonal antibody, clone MEM-241
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant CD4.
Immunogen
Recombinant Fc fusion protein corresponding to 2 N-terminus domains of human CD4.
Host
Mouse
Theoretical MW (kDa)
55
Reactivity
Human
Specificity
This antibody recognizes CD4 antigen, a 55 KDa transmebrane glycoprotein expressed on a subset of T lymphocytes (helper T-cells) and also on monocytes, tissue macrophages and granulocytes.
Form
Liquid
Isotype
IgG1
Recommend Usage
Flow Cytometry (1 ug/mL)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Flow Cytometry
Surface staining of human peripheral blood cells with CD4 monoclonal antibody, clone MEM-241 (Cat # MAB3837) conjugated with FITC. -
Gene Info — CD4
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Interactomes
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Pathways
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Diseases
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Publication Reference
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CD molecules 2006--human cell differentiation molecules.
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, Boumsell L, D Buckley C, Buhring HJ, Clark G, Engel P, Fox D, Jin BQ, Macardle PJ, Malavasi F, Mason D, Stockinger H, Yang X.
Journal of Immunological Methods 2007 Jan; 319(1-2):1.
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LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling.
Brdickova N, Brdicka T, Angelisova P, Horvath O, Spicka J, Hilgert I, Paces J, Simeoni L, Kliche S, Merten C, Schraven B, Horejsi V.
The Journal of Experimental Medicine 2003 Nov; 198(10):1453.
Application:Func, Human, Peripheral blood T cells.
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Cell surface receptors, virus entry and tropism of primate lentiviruses.
Clapham PR, McKnight A.
The Journal of General Virology 2002 Aug; 83(Pt 8):1809.
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CD molecules 2006--human cell differentiation molecules.
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