RIPK2 monoclonal antibody, clone Nick-1
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More Files
- More Functions
Western Blot (Cell lysate)
Detection of endogenous human RIPK2 in different human cell lines by RIPK2 monoclonal antibody, clone Nick-1 (Cat # MAB3727). Total cell extracts (50 ug) from Jurkat (lane 1), THP-1 (lane 2) and HT-1080 (lane 3).
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Specification
Product Description
Rat monoclonal antibody raised against partial recombinant RIPK2.
Immunogen
Recombinant protein corresponding to amino acids 1-322 of human RIPK2.
Host
Rat
Reactivity
Human
Specificity
Recognizes human RIP2.
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Detection of endogenous human RIPK2 in different human cell lines by RIPK2 monoclonal antibody, clone Nick-1 (Cat # MAB3727). Total cell extracts (50 ug) from Jurkat (lane 1), THP-1 (lane 2) and HT-1080 (lane 3). -
Gene Info — RIPK2
Entrez GeneID
8767Gene Name
RIPK2
Gene Alias
CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
Gene Description
receptor-interacting serine-threonine kinase 2
Omim ID
603455Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq
Other Designations
CARD-carrying kinase|CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase|growth-inhibiting gene 30|receptor interacting protein 2|receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP
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Interactome
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Pathway
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Disease
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