ABCC6 monoclonal antibody, clone M6II-31
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rat monoclonal antibody raised against recombinant ABCC6.
Immunogen
Recombinant protein corresponding to amino acids 764-964 of human ABCC6.
Host
Rat
Reactivity
Human
Specificity
M6II-31 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MPR4 and MRP5 gene products.
Form
Liquid
Isotype
IgG2a
Recommend Usage
Immunocytochemistry (1:20-50)
Western Blot (1:20-50)
Immunohistochemistry (Frozen sections) (1:20-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Immunocytochemistry
Flow Cytometry
-
Gene Info — ABCC6
Entrez GeneID
368Gene Name
ABCC6
Gene Alias
ABC34, ARA, EST349056, MLP1, MOATE, MRP6, PXE, PXE1
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family C, member 6|anthracycline resistance-associated
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
MRP6 (ABCC6) detection in normal human tissues and tumors.
Scheffer GL, Hu X, Pijnenborg AC, Wijnholds J, Bergen AA, Scheper RJ.
Laboratory Investigation 2002 Apr; 82(4):515.
Application：IHC, WB-Tr, Human, HEK 293 cells, Kidneys, Livers.
-
Mutations in ABCC6 cause pseudoxanthoma elasticum.
Bergen AA, Plomp AS, Schuurman EJ, Terry S, Breuning M, Dauwerse H, Swart J, Kool M, van Soest S, Baas F, ten Brink JB, de Jong PT.
Nature Genetics 2000 Jun; 25(2):228.
-
MRP6 (ABCC6) detection in normal human tissues and tumors.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com