ABCC3 monoclonal antibody, clone M3II-9

Catalog # MAB3384

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Size:500 uL
Price: USD $ 747.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Mouse monoclonal antibody raised against partial recombinant ABCC3.

    Immunogen

    Recombinant fusion protein corresponding to amino acids 830-949 of human ABCC3.

    Host

    Mouse

    Reactivity

    Human

    Specificity

    M3II-9 reacts with an internal epitope of human MRP-3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. Does not cross-react with human MDR1, MRP1, MRP2 or MRP-5 gene products.

    Form

    Liquid

    Isotype

    IgG1

    Recommend Usage

    Immunocytochemistry (1:20-1:50)
    Immunohistochemistry (Frozen sections) (1:20)
    Western Blot (1:20-1:50)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

    Immunohistochemistry (Frozen sections)

    Immunocytochemistry

    Flow Cytometry

  • Gene Info — ABCC3

    Entrez GeneID

    8714

    Gene Name

    ABCC3

    Gene Alias

    ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2

    Gene Description

    ATP-binding cassette, sub-family C (CFTR/MRP), member 3

    Omim ID

    604323

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq

    Other Designations

    ATP-binding cassette, sub-family C, member 3|canicular multispecific organic anion transporter|multidrug resistance associated protein

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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