MYD88 monoclonal antibody, clone 2E9C2
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant MYD88.
Immunogen
Recombinant protein corresponding to amino acids 176-280 of human MYD88.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (2-4 mg/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MYD88 in EL4 whole cell lysate with MYD88 monoclonal antibody, clone 2E9C2 (Cat # MAB2745) at 2 mg/ml.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of MYD88 in human heart with MYD88 monoclonal antibody, clone 2E9C2 (Cat # MAB2745) at 2.5 ug/mL . -
Gene Info — MYD88
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Interactome
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Pathway
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Disease
- Arthritis
- Asthma
- Birth Weight
- Cardiovascular Diseases
- Chronic Disease
- Coronary Disease
- Cystitis
- Diabetes Mellitus
- Edema
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Publication Reference
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Unresponsiveness of MyD88-deficient mice to endotoxin.
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S.
Immunity 1999 Jul; 11(1):115.
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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.
Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, Ghosh S, Janeway CA Jr.
Molecular Cell 1998 Aug; 2(2):253.
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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.
Adachi O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, Nakanishi K, Akira S.
Immunity 1998 Jul; 9(1):143.
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Unresponsiveness of MyD88-deficient mice to endotoxin.
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