ALYREF monoclonal antibody, clone 11G5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant ALYREF.
Immunogen
Recombinant protein corresponding to human ALYREF.
Host
Mouse
Theoretical MW (kDa)
32
Reactivity
Clawed frog, Human
Specificity
Detects a band of approximately 32 KDa.
Form
Liquid
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunofluorescence
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ALYREF
Entrez GeneID
10189Gene Name
ALYREF
Gene Alias
ALY, ALY/REF, BEF, REF, THOC4
Gene Description
Aly/REF export factor
Omim ID
604171Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq
Other Designations
THO complex 4; THO complex subunit 4; ally of AML-1 and LEF-1; bZIP enhancing factor; bZIP-enhancing factor BEF; tho4; transcriptional coactivator Aly/REF
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Interactome
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Publication Reference
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ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56.
Taniguchi I, Ohno M.
Molecular and Cellular Biology 2008 Jan; 28(2):601.
Application：IP, Frog, Frog RNA.
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The Y14 protein communicates to the cytoplasm the position of exon-exon junctions.
Kim VN, Yong J, Kataoka N, Abel L, Diem MD, Dreyfuss G.
The EMBO Journal 2001 Apr; 20(8):2062.
Application：IP-WB, WB-Ce, Human, Xenopus, HeLa cells, Oocytes.
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ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56.
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