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Last updated: 2014/9/15
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CTSL1 monoclonal antibody, clone 2H7

  • Catalog # : MAB2047
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CTSL1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 114-333 of human CTSL1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.1% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • The recombinant fusion proteins and cell lysate were resolved by SDS-PAGE and probed with CTSL1 monoclonal antibody, clone 2H7 (Cat # MAB2047) (1:1000).
    Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
    Lane 1 : CTSB.
    Lane 2 : CTSD.
    Lane 3 : CTSK.
    Lane 4 : CTSL1.
    Lane 5 : CTSS.
    Lane 6 : A-549.
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1514
  • Gene Name:
  • CTSL1
  • Gene Alias:
  • CATL,CTSL,FLJ31037,MEP
  • Gene Description:
  • cathepsin L1
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021601,OTTHUMP00000021602,OTTHUMP00000063566,cathepsin L,major excreted protein
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