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Last updated: 2014/8/18
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PGR monoclonal antibody, clone hPRa2+hPRa3

  • Catalog # : MAB1975
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native PGR.
  • Immunogen:
  • Native purified human PGR.
  • Host:
  • Mouse
  • Reactivity:
  • Horse, Human, Pig
  • Form:
  • Liquid
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody Reactive Against Native Purified Protein.
  • Recommend Usage:
  • Western blot (1 ug/mL)
    Immunoprecipitation (2 ug/mg of protein lysate)
    Immunohistochemistry on frozen and formalin to fixed/paraffin to embedded tissues (2 to 4 ug/mL)
    The optimal working dilution should be determined by the end
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining using PGR monoclonal antibody, clone hPRa2+hPRa3 (Cat # MAB1975) on formalin fixed, paraffin embedded human breast carcinoma.
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 5241
  • Gene Name:
  • PGR
  • Gene Alias:
  • NR3C3,PR
  • Gene Description:
  • progesterone receptor
  • Gene Summary:
  • This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
  • Other Designations:
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