CFB monoclonal antibody, clone KT21
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native CFB.
Immunogen
Native Purified human CFB.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Quality Control Testing
Antibody Reactive Against Native Purified Protein.
Recommend Usage
ELISA (1 ug/mL)
Sandwich ELISA (Capture: 5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Enzyme-linked Immunoabsorbent Assay
Sandwich ELISA
-
Gene Info — CFB
Entrez GeneID
629Gene Name
CFB
Gene Alias
BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2
Gene Description
complement factor B
Gene Ontology
HyperlinkGene Summary
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq
Other Designations
B-factor, properdin|C3 proaccelerator|C3 proactivator|C3/C5 convertase|OTTHUMP00000029283|OTTHUMP00000174690|glycine-rich beta-glycoprotein
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com