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Last updated: 2014/7/7
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CBL monoclonal antibody, clone M159

  • Catalog # : MAB1378
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of CBL.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CBL.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This sequence is highly conserved in rat and mouse c-Cbl.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:2000)
    Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of human Jurkat cells untreated (lane 1) or treated with pervanadate (1 mM) for 30 minutes (lane 2). The blot was probed with CBL monoclonal antibody, clone M159 (Cat # MAB1378).
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 867
  • Gene Name:
  • CBL
  • Gene Alias:
  • C-CBL,CBL2,RNF55
  • Gene Description:
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence
  • Gene Summary:
  • The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
  • Other Designations:
  • oncogene CBL2
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