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Last updated: 2014/11/23
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TLR2 monoclonal antibody, clone 1F10

  • Catalog # : MAB1081
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TLR2.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 221-384 of human TLR2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.1% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Toll-like receptors.
    Takeda K, Kaisho T, Akira S.Annu Rev Immunol. 2003;21:335-76. Epub 2001 Dec 19.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot of Ramos and A-549 cell lysates (20 ug) were resolved by SDS - PAGE , transferred to PVDF membrane and probed with TLR2 monoclonal antibody , clone 1F10 (1 : 500) (Cat # MAB1081). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7097
  • Gene Name:
  • TLR2
  • Gene Alias:
  • CD282,TIL4
  • Gene Description:
  • toll-like receptor 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
  • Other Designations:
  • toll/interleukin 1 receptor-like 4
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