FES monoclonal antibody, clone 2E3G3
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis using FES monoclonal antibody, clone 2E3G3 (Cat # MAB10646) against truncated FES recombinant protein.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human cerebrum tumor (upper) , endothelium of vessel (middle) , lymphocyte of thymus (bottom) , showing cytoplasmic localization using FES monoclonal antibody, clone 2E3G3 (Cat # MAB10646) with DAB staining.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant FES.
Immunogen
Recombinant protein corresponding to human FES.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using FES monoclonal antibody, clone 2E3G3 (Cat # MAB10646) against truncated FES recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human cerebrum tumor (upper) , endothelium of vessel (middle) , lymphocyte of thymus (bottom) , showing cytoplasmic localization using FES monoclonal antibody, clone 2E3G3 (Cat # MAB10646) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FES
Entrez GeneID
2242Gene Name
FES
Gene Alias
FPS
Gene Description
feline sarcoma oncogene
Omim ID
190030Gene Ontology
HyperlinkGene Summary
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms
Other Designations
Oncogene FES, feline sarcoma virus|c-fes/fps protein|feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog|proto-oncogene tyrosine-protein kinase Fes/Fps
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Interactome
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Pathway
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Disease
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