Western blot analysis using EPHA7 monoclonal antibody, clone 6C8G7 (Cat # MAB10597) against truncated GST-EPHA7 recombinant protein (1) and truncated EPHA7 (aa 25-556) -hIgGFc transfected CHOK1 cell lysate (2) .
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq