Immunohistochemical analysis of paraffin-embedded human ovarian cancer (A) and breast cancer (B) tissues using ATP2C1 monoclonal antibody, clone 4G12 (Cat # MAB10496) with DAB staining.
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq