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ATF2 monoclonal antibody, clone 4F12

  • Catalog # : MAB10494
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ATF2.
  • Immunogen:
  • Recombinant protein corresponding to human ATF2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 55
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using ATF2 monoclonal antibody, clone 4F12 (Cat # MAB10494) against NIH/3T3 cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and brain tissues (B) using ATF2 monoclonal antibody, clone 4F12 (Cat # MAB10494) with DAB staining.
  • ELISA
  • ELISA
  • ELISA detection with ATF2 monoclonal antibody, clone 4F12 (Cat # MAB10494).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1386
  • Gene Name:
  • ATF2
  • Gene Alias:
  • CRE-BP1,CREB2,HB16,MGC111558,TREB7
  • Gene Description:
  • activating transcription factor 2
  • Gene Summary:
  • This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000163262,activating transcription factor 2 splice variant ATF2-var2,cAMP responsive element binding protein 2, formerly
  • Gene Pathway
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