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Last updated: 2014/12/21

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AGT monoclonal antibody, clone 1B1

  • Catalog # : MAB10442
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant AGT.
  • Immunogen:
  • Recombinant protein corresponding to human AGT.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 53
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascitic (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis using AGT monoclonal antibody, clone 1B1 (Cat # MAB10442) against human plasma (1).
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 183
  • Gene Name:
  • AGT
  • Gene Alias:
  • ANHU,FLJ92595,FLJ97926,SERPINA8
  • Gene Description:
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Gene Summary:
  • The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035878,alpha-1 antiproteinase, antitrypsin,angiotensin I,angiotensin II,angiotensinogen,pre-angiotensinogen,serine (or cysteine) proteinase inhibitor
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