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EIF4EBP1 monoclonal antibody, clone 4B6G10

  • Catalog # : MAB10436
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant EIF4EBP1.
  • Immunogen:
  • Recombinant protein corresponding to human EIF4EBP1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascitic (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis using EIF4EBP1 monoclonal antibody, clone 4B6G10 (Cat # MAB10436) against truncated EIF4EBP1 recombinant protein (1) and A-431 cell lysate (2).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma (A), esophagus carcinoma tissue (B) and ovary tumor tissue (C), showing cytoplasmic and membrane localization using EIF4EBP1 monoclonal antibody, clone 4B6G10 (Cat # MAB10436) with DAB staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1978
  • Gene Name:
  • EIF4EBP1
  • Gene Alias:
  • 4E-BP1,4EBP1,BP-1,MGC4316,PHAS-I
  • Gene Description:
  • eukaryotic translation initiation factor 4E binding protein 1
  • Gene Summary:
  • This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq
  • Other Designations:
  • eIF4E-binding protein 1,phosphorylated heat- and acid-stable protein regulated by insulin 1
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