Mouse monoclonal antibody raised against native A2M.
Immunogen:
Native purified human A2M.
Host:
Mouse
Reactivity:
Human
Form:
Liquid
Isotype:
IgG1, kappa
Recommend Usage:
Western Blot (1:2000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Applications
Western Blot (Tissue lysate)
Immunoblot analysis of human plasma protein. Lane 1 : Alpha 2-macroglobulin isolated from human plasma. Lane 2 : Human plasma. (* N. S : Nonspecific band)
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq