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Last updated: 2014/11/23
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SERPINC1 monoclonal antibody, clone 8C12

  • Catalog # : MAB0743
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native SERPINC1.
  • Immunogen:
  • Native purified human SERPINC1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Immunoblot analysis of human plasma protein. Lane 1 : Antithrombin III isolated from human plasma. Lane 2 : Human plasma.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 462
  • Gene Name:
  • SERPINC1
  • Gene Alias:
  • AT3,ATIII,MGC22579
  • Gene Description:
  • serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Gene Summary:
  • The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035393,antithrombin (aa 375-432),antithrombin III,coding sequence signal peptide antithrombin part 1,serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1,signal peptide antithrombin part 1
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