S100A8 (Human) ELISA Kit
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More Files
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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
S100A8 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human S100A8/MRP8 in serum, plasma, and other biological media.
Suitable Sample
Biological Medium, Plasma, Serum
Sample Volume
100 uL (1:100 prediluted)
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
3.75%
Inter-Assay
5.16%
Calibration Range
78.1 to 5000 pg/mL
Limit of Detection
43.4 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C away from light.
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Applications
Quantification
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Gene Info — S100A8
Entrez GeneID
6279Gene Name
S100A8
Gene Alias
60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8
Gene Description
S100 calcium binding protein A8
Omim ID
123885Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq
Other Designations
OTTHUMP00000015329|OTTHUMP00000015330|S100 calcium-binding protein A8|S100 calcium-binding protein A8 (calgranulin A)|calgranulin A|cystic fibrosis antigen
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Interactome
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Disease
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Publication Reference
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Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis.
Foell D, Hernandez-Rodriguez J, Sanchez M, Vogl T, Cid MC, Roth J.
The Journal of Pathology 2004 Nov; 204(3):311.
Application：Quant, Human, Human serum.
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S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity.
Nacken W, Roth J, Sorg C, Kerkhoff C.
Microscopy Research and Technique 2003 Apr; 60(6):569.
Application：Quant, Human, Human plasma.
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Il-10 up-regulates macrophage expression of the S100 protein S100A8.
K Xu, T Yen, C L Geczy.
Journal of Immunology 2001 May; 166(10):6358.
Application：Quant, Mouse, Raw 264.7 cells.
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Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis.
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