IL5 (Human) ELISA Kit
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Specification
Product Description
IL5 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human IL5.
Suitable Sample
Cell culture supernates, Plasma (heparin, EDTA), Serum and Urine
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
7.8 to 500 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — IL5
Entrez GeneID
3567Gene Name
IL5
Gene Alias
EDF, IL-5, TRF
Gene Description
interleukin 5 (colony-stimulating factor, eosinophil)
Omim ID
147850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq
Other Designations
B cell differentiation factor I|OTTHUMP00000065830|T-cell replacing factor|eosinophil differentiation factor|interleukin 5|interleukin-5
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Interactome
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Publication Reference
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Mutation analysis of interleukin-5 in an asthmatic cohort.
Pereira E, Goldblatt J, Rye P, Sanderson C, Le Souef P.
Human Mutation 1998 Jan; 11(1):51.
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Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).
Le Beau MM, Lemons RS, Espinosa R 3rd, Larson RA, Arai N, Rowley JD.
Blood 1989 Feb; 73(3):647.
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Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5).
Campbell HD, Tucker WQ, Hort Y, Martinson ME, Mayo G, Clutterbuck EJ, Sanderson CJ, Young IG.
PNAS 1987 Oct; 84(19):6629.
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Mutation analysis of interleukin-5 in an asthmatic cohort.
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