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Last updated: 2014/11/16
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Caspase-5 Inhibitor Screening Kit

  • Catalog # : KA0750
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  • Specification
  • Product Description:
  • Caspase-5 Inhibitor Screening Kit is used for screening caspase inhibitors using fluorometric methods.
  • Reactivity:
  • Mammals
  • Storage Instruction:
  • Store the kit at -20°C.
  • Suitable Sample:
  • Cell
  • Detection Method:
  • Fluorometric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 838
  • Gene Name:
  • CASP5
  • Gene Alias:
  • ICE(rel)III,ICEREL-III,ICH-3,MGC141966
  • Gene Description:
  • caspase 5, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000045729,TY protease,caspase 5,caspase 5, apoptosis-related cysteine protease
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