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Last updated: 2014/10/27
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Caspase-4 Assay Kit (Colorimetric)

  • Catalog # : KA0745
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  • Specification
  • Product Description:
  • Caspase-4 Assay Kit (Colorimetric) is used for detecting the activity of caspases that recognize the sequence LEVD using colorimetric method.
  • Reactivity:
  • Mammals
  • Storage Instruction:
  • Store the kit at -20°C.
  • Suitable Sample:
  • Cell Lysate, Tissue Lysate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 837
  • Gene Name:
  • CASP4
  • Gene Alias:
  • ICE(rel)II,ICEREL-II,ICH-2,Mih1/TX,TX
  • Gene Description:
  • caspase 4, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • apoptotic cysteine protease Mih1/TX,caspase 4,caspase 4, apoptosis-related cysteine protease
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