FGF2 (Human) ELISA Kit
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Specification
Product Description
FGF2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human FGF2.
Suitable Sample
Cell Culture Supernatant, Plasma, Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
6.39%
Inter-Assay
4.69%
Spiking Recovery
Serum: 94.00%, Plasma: 102.00%, Cell Culture Supernatant: 108.00%
Calibration Range
78 to 8000 pg/mL
Limit of Detection
78 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — FGF2
Entrez GeneID
2247Gene Name
FGF2
Gene Alias
BFGF, FGFB, HBGF-2
Gene Description
fibroblast growth factor 2 (basic)
Omim ID
134920Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq
Other Designations
basic fibroblast growth factor bFGF|fibroblast growth factor 2|heparin-binding growth factor 2|prostatropin
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Interactome
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Publication Reference
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Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor.
Barrandon Y, Green H.
Cell 1987 Sep; 50(7):1131.
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Physiological effects of transforming growth factor in the newborn mouse.
Tam JP.
Science 1985 Aug; 229(4714):673.
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Human transforming growth factor-alpha causes precocious eyelid opening in newborn mice.
Smith JM, Sporn MB, Roberts AB, Derynck R, Winkler ME, Gregory H.
Nature 1985 Jun; 315(6019):515.
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Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor.
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