A2M (Human) ELISA Kit
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Specification
Product Description
A2M (Human) ELISA Kit is a competitive enzyme immunoassay for the quantitative measurement of human A2M in plasma and serum.
Suitable Sample
Plasma, Serum
Sample Volume
25 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
1.25 to 40 ug/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — A2M
Entrez GeneID
2Gene Name
A2M
Gene Alias
CPAMD5, DKFZp779B086, FWP007, S863-7
Gene Description
alpha-2-macroglobulin
Gene Ontology
HyperlinkGene Summary
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia.
Liu LY, Yang T, Ji J, Wen Q, Morgan AA, Jin B, Chen G, Lyell DJ, Stevenson DK, Ling XB, Butte AJ.
BMC Medicine 2013 Nov; 11(1):236.
Application:ELISA, Human, Serum.
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Assessing candidate serum biomarkers for Alzheimer's disease: a longitudinal study.
Zabel M, Schrag M, Mueller C, Zhou W, Crofton A, Petersen F, Dickson A, Kirsch WM.
Journal of Alzheimer's Disease 2012 May; 30(2):311.
Application:ELISA, Human, Serum.
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Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis.
Pineda-Salgado L, Craig EJ, Blank RB, Kessler DS.
Gene Expression Patterns 2015 Dec; 6(1):3.
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Glomerular deposition of alpha 2-macroglobulin in glomerular diseases.
Yang AH, Chen JY.
Nephrology, Dialysis, Transplantation 1997 Mar; 12(3):465.
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Hepatocyte growth factor and acute phase proteins in patients with chronic liver diseases.
Shiota G, Umeki K, Okano J, Kawasaki H.
J Med 1995 Jan; 26(5-6):295.
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Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia.
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