TNFRSF1B (Human) ELISA Kit
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
TNFRSF1B (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human TNFRSF1B.
Suitable Sample
Body Fluid, Cell Culture Supernatant, Plasma, Serum, Tissue Lysate
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
7.8 to 500 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
-
Applications
Quantification
-
Gene Info — TNFRSF1B
Entrez GeneID
7133Gene Name
TNFRSF1B
Gene Alias
CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Gene Description
tumor necrosis factor receptor superfamily, member 1B
Omim ID
191191Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq
Other Designations
OTTHUMP00000001784|p75 TNF receptor|soluble TNFR1B variant 1|tumor necrosis factor beta receptor|tumor necrosis factor binding protein 2|tumor necrosis factor receptor 2
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization.
Santee SM, Owen-Schaub LB.
The Journal of Biological Chemistry 1996 Aug; 271(35):21151.
-
Physical mapping and genomic structure of the human TNFR2 gene.
Beltinger CP, White PS, Maris JM, Sulman EP, Jensen SJ, LePaslier D, Stallard BJ, Goeddel DV, de Sauvage FJ, Brodeur GM.
Genomics 1996 Jul; 35(1):94.
-
Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com