IL27 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IL27 protein.
Immunogen
IL27 (AAH62422.1, 1 a.a. ~ 243 a.a) full-length human protein.
Sequence
MGQTAGDLGWRLSLLLLPLLLVQAGVWGFPRPPGRPQLSLQELRREFTVSLHLARKLLAEVRGQAHRFAESHLPGVNLYLLPLGEQLPDVSLTFQAWRRLSDPERLCFISTTLQPFHALLGGLGTQGRWTNMERMQLWAMRLDLRDLQRHLRFQVLAAGFNLPEEEEEEEEEEEEERKGLLPGALGSALQGPAQVSWPQLLSTYRLLHSLELVLSRAVRELLLLSKAGHSVWPLGFPTLSPQP
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL27 expression in transfected 293T cell line (H00246778-T02) by IL27 MaxPab polyclonal antibody.
Lane 1: IL27 transfected lysate(27.50 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of IL27 transfected lysate using anti-IL27 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL27 purified MaxPab mouse polyclonal antibody (B01P) (H00246778-B01P). -
Gene Info — IL27
Entrez GeneID
246778GeneBank Accession#
BC062422Protein Accession#
AAH62422.1Gene Name
IL27
Gene Alias
IL-27, IL-27A, IL27p28, IL30, MGC71873, p28
Gene Description
interleukin 27
Omim ID
608273Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq
Other Designations
IL-27 p28 subunit|OTTHUMP00000122516|interleukin 30|interleukin-27 subunit alpha
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Disease
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