HTRA4 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of HTRA4 expression in transfected 293T cell line (H00203100-T02) by HTRA4 MaxPab polyclonal antibody.
Lane 1: HTRA4 transfected lysate(52.36 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HTRA4 protein.
Immunogen
HTRA4 (AAH57765.1, 1 a.a. ~ 476 a.a) full-length human protein.
Sequence
MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVFEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HTRA4 expression in transfected 293T cell line (H00203100-T02) by HTRA4 MaxPab polyclonal antibody.
Lane 1: HTRA4 transfected lysate(52.36 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HTRA4
Entrez GeneID
203100GeneBank Accession#
BC057765Protein Accession#
AAH57765.1Gene Name
HTRA4
Gene Alias
FLJ90724
Gene Description
HtrA serine peptidase 4
Omim ID
610700Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq
Other Designations
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Interactome
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Publication Reference
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HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4.
Mary Mansilla, Yao Wang, Rebecca Lim, Kirsten Palmer, Guiying Nie.
Scientific Reports 2021 Jul; 11(1):14363.
Application：WB, Human, BeWo Cell.
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HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4.
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