FGD5 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FGD5 expression in transfected 293T cell line (H00152273-T01) by FGD5 MaxPab polyclonal antibody.
Lane 1: FGD5 transfected lysate(59.4 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human FGD5 protein.
Immunogen
FGD5 (AAH35364.1, 1 a.a. ~ 540 a.a) full-length human protein.
Sequence
MRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLYTYPQKDGKYRLKNTLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQALAAFHHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSGSAFSSVFQSINPSTFKKQKKVPSALTEVAASGEGSAISGYLSRCKRGKRHWKKLWFVIKGKVLYTYMASEDKVALESMPLLGFTIAPEKEEGSSEVGPIFHLYHKKTLFYSFKAEDTNSAQRWIEAMEDASVL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FGD5 expression in transfected 293T cell line (H00152273-T01) by FGD5 MaxPab polyclonal antibody.
Lane 1: FGD5 transfected lysate(59.4 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FGD5
Entrez GeneID
152273GeneBank Accession#
BC035364.1Protein Accession#
AAH35364.1Gene Name
FGD5
Gene Alias
ZFYVE23
Gene Description
FYVE, RhoGEF and PH domain containing 5
Gene Ontology
HyperlinkGene Summary
O
Other Designations
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Interactome
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Publication Reference
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VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
Braun LJ, Zinnhardt M, Vockel M, Drexler HC, Peters K, Vestweber D.
EMBO reports 2019 Jul; 20(7):e47046.
Application：IF, IP-WB, WB-Ce, WB-Ti, WB-Tr, Human, Mouse, HUVECs, Lung.
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Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization.
Ando K, Fukuhara S, Moriya T, Obara Y, Nakahata N, Mochizuki N.
Journal of Cell Biology 2013 Sep; 202(6):901.
Application：WB, Human, HUVEC.
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FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells.
Kurogane Y, Miyata M, Kubo Y, Nagamatsu Y, Kundu RK, Uemura A, Ishida T, Quertermous T, Hirata K, Rikitake Y.
Arteriosclerosis, Thrombosis, and Vascular Biology 2012 Apr; 32(4):988.
Application：IF, WB-Ce, WB-Tr, Human, HAECs, HCAECs, HMVECs, HUVECs.
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VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
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