RDH12 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human RDH12 partial ORF ( NP_689656.1, 217 a.a. - 316 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
RLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGIRWE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RDH12
Entrez GeneID
145226GeneBank Accession#
NM_152443Protein Accession#
NP_689656.1Gene Name
RDH12
Gene Alias
FLJ30273, LCA3, SDR7C2
Gene Description
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq
Other Designations
retinol dehydrogenase 12|retinol dehydrogenase 12, all-trans and 9-cis|short chain dehydrogenase/reductase family 7C, member 2
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Interactome
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Pathway
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Disease
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