RDH12 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of RDH12 expression in transfected 293T cell line (H00145226-T01) by RDH12 MaxPab polyclonal antibody.
Lane 1: RDH12 transfected lysate(34.76 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RDH12 protein.
Immunogen
RDH12 (NP_689656.1, 1 a.a. ~ 316 a.a) full-length human protein.
Sequence
MLVTLGLLTSFFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLEQLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGIRWE
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RDH12 expression in transfected 293T cell line (H00145226-T01) by RDH12 MaxPab polyclonal antibody.
Lane 1: RDH12 transfected lysate(34.76 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RDH12
Entrez GeneID
145226GeneBank Accession#
NM_152443.1Protein Accession#
NP_689656.1Gene Name
RDH12
Gene Alias
FLJ30273, LCA3, SDR7C2
Gene Description
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq
Other Designations
retinol dehydrogenase 12|retinol dehydrogenase 12, all-trans and 9-cis|short chain dehydrogenase/reductase family 7C, member 2
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Interactome
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Pathway
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Disease
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