PPIL5 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PPIL5 expression in transfected 293T cell line (H00122769-T03) by PPIL5 MaxPab polyclonal antibody.
Lane 1: PPIL5 transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PPIL5 protein.
Immunogen
PPIL5 (NP_689542.2, 1 a.a. ~ 414 a.a) full-length human protein.
Sequence
MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRYELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPVSTLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQPKVLPVIKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYVNSSDMLK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (77)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PPIL5 expression in transfected 293T cell line (H00122769-T03) by PPIL5 MaxPab polyclonal antibody.
Lane 1: PPIL5 transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PPIL5
Entrez GeneID
122769GeneBank Accession#
NM_152329.3Protein Accession#
NP_689542.2Gene Name
PPIL5
Gene Alias
4-1BBLRR, LRR-1, MGC20689
Gene Description
peptidylprolyl isomerase (cyclophilin)-like 5
Omim ID
609193Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
4-1BB-mediated signaling molecule|LRR-repeat protein 1|cyclophilin-like 5|peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3
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