MARS2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human MARS2 partial ORF ( NP_612404, 1 a.a. - 106 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLRTSVLRLLGRTGASRLSLLEDFGPRYYSSGSLSAGDDACDVRAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.4
Interspecies Antigen Sequence
Mouse (71); Rat (73)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MARS2
Entrez GeneID
92935GeneBank Accession#
NM_138395Protein Accession#
NP_612404Gene Name
MARS2
Gene Alias
MetRS, mtMetRS
Gene Description
methionyl-tRNA synthetase 2, mitochondrial
Omim ID
609728Gene Ontology
HyperlinkGene Summary
O
Other Designations
methionine tRNA ligase 2, mitochondrial|methionine-tRNA ligase|methionine-tRNA synthetase 2|methionine-tRNA synthetase 2 (mitochondrial)|methionine-tRNA synthetase 2, mitochondrial|mitochondrial methionyl-tRNA synthetase
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Interactome
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Pathway
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Publication Reference
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Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans.
Bayat V, Thiffault I, Jaiswal M, Tétreault M, Donti T, Sasarman F, Bernard G, Demers-Lamarche J, Dicaire MJ, Mathieu J, Vanasse M, Bouchard JP, Rioux MF, Lourenco CM, Li Z, Haueter C, Shoubridge EA, Graham BH, Brais B, Bellen HJ.
PLoS Biology 2012 Mar; 10(3):e1001288.
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Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans.
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