NDEL1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of NDEL1 expression in transfected 293T cell line (H00081565-T01) by NDEL1 MaxPab polyclonal antibody.
Lane 1: NDEL1 transfected lysate(38.40 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NDEL1 protein.
Immunogen
NDEL1 (NP_110435.1, 1 a.a. ~ 345 a.a) full-length human protein.
Sequence
MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NDEL1 expression in transfected 293T cell line (H00081565-T01) by NDEL1 MaxPab polyclonal antibody.
Lane 1: NDEL1 transfected lysate(38.40 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — NDEL1
Entrez GeneID
81565GeneBank Accession#
NM_030808Protein Accession#
NP_110435.1Gene Name
NDEL1
Gene Alias
DKFZp451M0318, EOPA, MITAP1, NUDEL
Gene Description
nudE nuclear distribution gene E homolog (A. nidulans)-like 1
Omim ID
607538Gene Ontology
HyperlinkGene Summary
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
NUDE-like protein|endooligopeptidase A|mitosin-associated protein MITAP1|nudE nuclear distribution gene E homolog like 1
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Interactome
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Disease
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Publication Reference
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The mechanism of acentrosomal spindle assembly in human oocytes.
Tianyu Wu, Jie Dong, Jing Fu, Yanping Kuang, Biaobang Chen, Hao Gu, Yuxi Luo, Ruihuan Gu, Meiling Zhang, Wen Li, Xi Dong, Xiaoxi Sun, Qing Sang, Lei Wang.
Science 2022 Nov; 378(6621):eabq7361.
Application：IF, Human, Human oocytes.
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A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes.
So C, Seres KB, Steyer AM, Mönnich E, Clift D, Pejkovska A, Möbius W, Schuh M.
Science 2019 Jun; 364(6447):eaat9557.
Application：IF, Bovine, Mouse, Ovine, Pig, NIH/3T3 cells, Oocytes.
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The mechanism of acentrosomal spindle assembly in human oocytes.
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