COLEC12 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and COLEC12 expressing 293 cells (Green) using COLEC12 purified MaxPab mouse polyclonal antibody.
Western Blot (Tissue lysate)
COLEC12 MaxPab polyclonal antibody. Western Blot analysis of COLEC12 expression in human placenta.
Western Blot (Transfected lysate)
Western Blot analysis of COLEC12 expression in transfected 293T cell line (H00081035-T01) by COLEC12 MaxPab polyclonal antibody.
Lane 1: COLEC12 transfected lysate(68.42 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human COLEC12 protein.
Immunogen
COLEC12 (NP_110408, 1 a.a. ~ 622 a.a) full-length human protein.
Sequence
MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYKVVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQQLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNLQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENITTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLTSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIMEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNSKSKPSLQPGGQGSACA
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and COLEC12 expressing 293 cells (Green) using COLEC12 purified MaxPab mouse polyclonal antibody.Western Blot (Tissue lysate)
COLEC12 MaxPab polyclonal antibody. Western Blot analysis of COLEC12 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of COLEC12 expression in transfected 293T cell line (H00081035-T01) by COLEC12 MaxPab polyclonal antibody.
Lane 1: COLEC12 transfected lysate(68.42 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — COLEC12
Entrez GeneID
81035GeneBank Accession#
NM_030781Protein Accession#
NP_110408Gene Name
COLEC12
Gene Alias
CLP1, NSR2, SCARA4, SRCL
Gene Description
collectin sub-family member 12
Omim ID
607621Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells. [provided by RefSeq
Other Designations
collectin placenta 1|nurse cell scavenger receptor 2|scavenger receptor class A, member 4|scavenger receptor with C-type lectin
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Interactome
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Disease
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Publication Reference
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Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.
Chang LL, Hsu WH, Kao MC, Chou CC, Lin CC, Liu CJ, Weng BC, Kuo FC, Kuo CH, Lin MH, Wang CJ, Lin CH, Wu DC, Huang SK.
Scientific Reports 2018 Feb; 8:3821.
Application：IF, IHC, Human, Primary gastric stromal cells (GSCs), gastric surgical tissue.
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Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.
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