GSDMD purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GSDMD protein.
Immunogen
GSDMD (NP_079012.3, 1 a.a. ~ 484 a.a) full-length human protein.
Sequence
MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLSIKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLSQEPH
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (57); Rat (54)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GSDMD expression in transfected 293T cell line (H00079792-T02) by GSDMD MaxPab polyclonal antibody.
Lane 1: GSDMD transfected lysate(52.80 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GSDMD
Entrez GeneID
79792GeneBank Accession#
NM_024736.5Protein Accession#
NP_079012.3Gene Name
GSDMD
Gene Alias
DF5L, FKSG10, FLJ12150, GSDMDC1
Gene Description
gasdermin D
Gene Ontology
HyperlinkOther Designations
1810036L03Rik|gasdermin domain containing 1
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Interactome
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Publication Reference
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Microparticulate Caspase-1 Regulates Gasdermin-D and Pulmonary Vascular Endothelial Cell Injury.
Mitra S, Exline M, Habyarimana F, Gavrilin M, Baker P, Masters SL, Wewers MD, Sarkar A.
American Journal of Respiratory Cell and Molecular Biology 2018 Jan; [Epub].
Application:IF, Human, THP1 cells.
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Microparticulate Caspase-1 Regulates Gasdermin-D and Pulmonary Vascular Endothelial Cell Injury.
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