PINK1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PINK1.
Immunogen
PINK1 (AAH28215, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag.
Sequence
FRLEEYLIGQSIGKGCSAAVYEATMPTLPQNLEVTKSTGLLPGRGPGTSAPGEGQERAAGAPAFPLAIKMMWNISAGSSSEAILNTMSQELVPASRVALA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (78)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PINK1
Entrez GeneID
65018GeneBank Accession#
BC028215Protein Accession#
AAH28215Gene Name
PINK1
Gene Alias
BRPK, FLJ27236, PARK6
Gene Description
PTEN induced putative kinase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq
Other Designations
OTTHUMP00000002881|protein kinase BRPK|serine/threonine-protein kinase PINK1
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Interactome
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Disease
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Publication Reference
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Comparative Gene Identification-58 (CGI-58) Promotes Autophagy as a Putative Lysophosphatidylglycerol Acyltransferase.
Zhang J, Xu D, Nie J, Han R, Zhai Y, Shi Y.
The Journal of Biological Chemistry 2014 Nov; 289(47):33044.
Application:WB-Tr, Mouse, C2C12 cells.
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Ablation of ALCAT1 mitigates hypertrophic cardiomyopathy through effects on oxidative stress and mitophagy.
Liu X, Ye B, Miller S, Yuan H, Zhang H, Tian L, Nie J, Imae R, Arai H, Li Y, Cheng Z, Shi Y.
Molecular and Cellular Biology 2012 Nov; 32(21):4493.
Application:WB-Ti, Mouse, Mouse ventricular tissues.
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Comparative Gene Identification-58 (CGI-58) Promotes Autophagy as a Putative Lysophosphatidylglycerol Acyltransferase.
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