RPTOR purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of RPTOR expression in transfected 293T cell line (H00057521-T04) by RPTOR MaxPab polyclonal antibody.
Lane 1: RPTOR transfected lysate(41.69 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RPTOR on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RPTOR protein.
Immunogen
RPTOR (AAH64515.1, 1 a.a. ~ 379 a.a) full-length human protein.
Sequence
MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNCIQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPGRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPPTYMHAMW
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RPTOR expression in transfected 293T cell line (H00057521-T04) by RPTOR MaxPab polyclonal antibody.
Lane 1: RPTOR transfected lysate(41.69 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RPTOR on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RPTOR
Entrez GeneID
57521GeneBank Accession#
BC064515Protein Accession#
AAH64515.1Gene Name
RPTOR
Gene Alias
KOG1, Mip1
Gene Description
regulatory associated protein of MTOR, complex 1
Omim ID
607130Gene Ontology
HyperlinkGene Summary
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats|regulatory associated protein of mTOR
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Interactome
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Pathway
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Disease
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